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PCDH8 has not been detected as a mutational cancer driver

PCDH8
Ensembl id ENSG00000136099
Mutated samples
Coding Sequence 67 (1.0%)
Protein Affecting 48 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PCDH8 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 10 9 2.30
Cutaneous melanoma No 17 9 2.44
Head and neck squamous cell carcinoma No 10 7 1.87
Lung squamous cell carcinoma No 7 6 3.45
Bladder carcinoma No 6 5 5.10
Stomach adenocarcinoma No 3 3 1.86
Esophageal carcinoma No 6 3 2.05
Prostate adenocarcinoma No 2 1 0.41
Breast carcinoma No 1 1 0.09
Thyroid carcinoma No 1 1 0.31
Neuroblastoma No 1 1 0.48
Non small cell lung carcinoma No 1 1 3.23
Serous ovarian adenocarcinoma No 1 1 0.32
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence