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NUP107 mutations in 11 cancer types possibly contribute to the detection of the gene in the PAN-cancer anlaysis:: Lung adenocarcinoma, Bladder carcinoma, Breast carcinoma, Lung squamous cell carcinoma, Cutaneous melanoma, Stomach adenocarcinoma, Small cell lung carcinoma, Colorectal adenocarcinoma, Head and neck squamous cell carcinoma, Glioblastoma multiforme

NUP107
Ensembl id ENSG00000111581
Mutated samples
Coding Sequence 68 (1.0%)
Protein Affecting 43 (0.6%)
Mode of action Activating
Known driver No
Cancer type Signals (Biases)
PAN
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all NUP107 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma Yes 16 8 2.17
Lung adenocarcinoma Yes 7 5 1.28
Bladder carcinoma Yes 6 5 5.10
Breast carcinoma Yes 7 5 0.44
Stomach adenocarcinoma Yes 8 4 2.48
Lung squamous cell carcinoma Yes 2 2 1.15
Small cell lung carcinoma Yes 3 2 2.90
Colorectal adenocarcinoma Yes 2 2 0.87
Head and neck squamous cell carcinoma Yes 2 2 0.53
Glioblastoma multiforme Yes 2 2 0.53
Esophageal carcinoma Yes 3 2 1.37
Prostate adenocarcinoma No 3 2 0.82
Renal clear cell carcinoma No 1 1 0.24
Uterine corpus endometrioid carcinoma No 2 1 0.43
Hepatocarcinoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence