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NRAS is detected as a mutational cancer driver in Prostate Adenocarcinoma

NRAS reports in Prostate Adenocarcinoma (PRAD)

Cancer type details
Prostate Adenocarcinoma
Cohorts 13
Samples 2,819
Mutations 9,128,298
Driver genes 104
Gene details
NRAS
Ensembl ID ENSG00000213281
Transcript ID ENST00000369535
Protein ID ENSP00000358548
Cohorts where is driver 1
Mutated samples 6
Mutated samples (%) 0.21
Mutations 9
Mode of action Activating
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence