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NR3C1 has not been detected as a mutational cancer driver

NR3C1
Ensembl id ENSG00000113580
Mutated samples
Coding Sequence 48 (0.7%)
Protein Affecting 37 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all NR3C1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 10 8 2.17
Head and neck squamous cell carcinoma No 6 6 1.60
Breast carcinoma No 4 4 0.35
Stomach adenocarcinoma No 5 4 2.48
Lung adenocarcinoma No 3 3 0.77
Uterine corpus endometrioid carcinoma No 4 3 1.30
Serous ovarian adenocarcinoma No 2 2 0.63
Hepatocarcinoma No 2 1 1.11
Bladder carcinoma No 1 1 1.02
Lung squamous cell carcinoma No 2 1 0.57
Multiple myeloma No 1 1 1.45
Lower grade glioma No 1 1 0.59
Small cell lung carcinoma No 1 1 1.45
Esophageal carcinoma No 1 1 0.68
Renal clear cell carcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Colorectal adenocarcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence