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NR2C2 has not been detected as a mutational cancer driver

NR2C2
Ensembl id ENSG00000177463
Mutated samples
Coding Sequence 41 (0.6%)
Protein Affecting 24 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all NR2C2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Stomach adenocarcinoma No 5 4 2.48
Bladder carcinoma No 3 3 3.06
Cutaneous melanoma No 5 3 0.81
Breast carcinoma No 5 2 0.17
Lung squamous cell carcinoma No 2 2 1.15
Head and neck squamous cell carcinoma No 2 2 0.53
Esophageal carcinoma No 2 2 1.37
Lung adenocarcinoma No 2 1 0.26
Renal clear cell carcinoma No 1 1 0.24
Uterine corpus endometrioid carcinoma No 1 1 0.43
Multiple myeloma No 1 1 1.45
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 3 1 0.26
Hepatocarcinoma No 4 0 0.00
Medulloblastoma No 1 0 0.00
Neuroblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence