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NPR2 has not been detected as a mutational cancer driver

NPR2
Ensembl id ENSG00000159899
Mutated samples
Coding Sequence 90 (1.3%)
Protein Affecting 39 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all NPR2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 24 9 2.44
Head and neck squamous cell carcinoma No 7 5 1.33
Breast carcinoma No 7 4 0.35
Lung squamous cell carcinoma No 5 4 2.30
Lung adenocarcinoma No 5 2 0.51
Renal clear cell carcinoma No 6 2 0.48
Uterine corpus endometrioid carcinoma No 5 2 0.87
Chronic lymphocytic leukemia No 3 2 0.69
Serous ovarian adenocarcinoma No 4 2 0.63
Stomach adenocarcinoma No 7 2 1.24
Small cell lung carcinoma No 2 2 2.90
Bladder carcinoma No 3 1 1.02
Colorectal adenocarcinoma No 4 1 0.44
Esophageal carcinoma No 2 1 0.68
Prostate adenocarcinoma No 1 0 0.00
Hepatocarcinoma No 1 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
Neuroblastoma No 1 0 0.00
Glioblastoma multiforme No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence