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NLRP13 has not been detected as a mutational cancer driver in this cancer type

Cutaneous melanoma
Projects 2
369 Samples
Coding sequence mutations (CSMs)
in driver genes 4035
in all genes 413513
Protein affecting mutations (PAMs)
in driver genes 2994
in all genes 167055
NLRP13
Ensembl id ENSG00000173572
Mutated samples
Coding Sequence 70 (19.0%)
Protein Affecting 43 (11.7%)
Mode of action Unclassified
Known driver No
Project Signals
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated Cutaneous melanoma projects in all NLRP13 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Project Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Skin cutaneous melanoma TCGA obtained from Synapse No 49 28 7.59
Skin cutaneous melanoma BROAD obtained from Alexandrov No 21 15 4.07
The mutations needle plot shows the distribution of the observed NLRP13 cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence Driver classification