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NKX2-1 is detected as a mutational cancer driver

NKX2-1 reports

Gene details
NKX2-1
Ensembl ID ENSG00000136352
Transcript ID ENST00000354822
Protein ID ENSP00000346879
Cancer types where is driver 1
Cohorts where is driver 1
Mutated samples 4
Mutations 110
Mode of action Ambiguous
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Mutation distribution
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence