NAF1 has not been detected as a mutational cancer driver

Ensembl id ENSG00000145414
Mutated samples
Coding Sequence 39 (0.6%)
Protein Affecting 28 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all NAF1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 8 7 1.90
Lung squamous cell carcinoma No 6 4 2.30
Head and neck squamous cell carcinoma No 4 4 1.07
Lung adenocarcinoma No 3 2 0.51
Renal clear cell carcinoma No 3 2 0.48
Serous ovarian adenocarcinoma No 2 2 0.63
Glioblastoma multiforme No 3 2 0.53
Bladder carcinoma No 1 1 1.02
Breast carcinoma No 1 1 0.09
Uterine corpus endometrioid carcinoma No 2 1 0.43
Lower grade glioma No 1 1 0.59
Esophageal carcinoma No 3 1 0.68
Medulloblastoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence