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MYOM3 has not been detected as a mutational cancer driver

MYOM3
Ensembl id ENSG00000142661
Mutated samples
Coding Sequence 140 (2.1%)
Protein Affecting 97 (1.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MYOM3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 57 40 10.84
Lung adenocarcinoma No 12 10 2.56
Breast carcinoma No 13 9 0.78
Bladder carcinoma No 10 7 7.14
Stomach adenocarcinoma No 9 6 3.73
Small cell lung carcinoma No 6 5 7.25
Lung squamous cell carcinoma No 6 4 2.30
Uterine corpus endometrioid carcinoma No 5 4 1.74
Lower grade glioma No 3 3 1.78
Renal clear cell carcinoma No 5 2 0.48
Thyroid carcinoma No 2 2 0.62
Neuroblastoma No 2 2 0.95
Serous ovarian adenocarcinoma No 2 2 0.63
Head and neck squamous cell carcinoma No 2 1 0.27
Prostate adenocarcinoma No 1 0 0.00
Acute myeloid leukemia No 2 0 0.00
Glioblastoma multiforme No 1 0 0.00
Esophageal carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence