MYH11 is detected as a mutational cancer driver in Small Cell Lung Cancer
MYH11 reports in Small Cell Lung Cancer (SCLC)
Cancer type details
| Small Cell Lung Cancer |
|---|
|
Cohorts
3
Samples 188 Mutations 2,426,920 Driver genes 24 |
Gene details
| MYH11 |
|---|
|
Ensembl ID
ENSG00000133392
Transcript ID ENST00000396324 Protein ID ENSP00000379616 |
|
Cohorts where is driver
1
Mutated samples 4 Mutated samples (%) 2.13 Mutations 6 |
| Mode of action Activating |
| Known driver True |
Method signals per Cohort
| Cohort | Methods | Samples | Samples (%) |
|---|
ClustL
HotMAPS
smRegions
Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed
mutations along the protein sequence.
| Mutation (GRCh38) | Protein Position | Samples | Samples (%) | Consequence |
|---|