Top
MTUS2 has not been detected as a mutational cancer driver

MTUS2
Ensembl id ENSG00000132938
Mutated samples
Coding Sequence 196 (2.9%)
Protein Affecting 130 (1.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MTUS2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 71 49 13.28
Lung adenocarcinoma No 18 14 3.58
Uterine corpus endometrioid carcinoma No 13 9 3.91
Lung squamous cell carcinoma No 14 8 4.60
Head and neck squamous cell carcinoma No 9 7 1.87
Glioblastoma multiforme No 7 6 1.58
Breast carcinoma No 9 5 0.44
Renal clear cell carcinoma No 6 5 1.20
Stomach adenocarcinoma No 8 5 3.11
Serous ovarian adenocarcinoma No 4 4 1.27
Esophageal carcinoma No 4 3 2.05
Bladder carcinoma No 4 2 2.04
Acute myeloid leukemia No 2 2 1.02
Pancreas adenocarcinoma No 2 2 0.93
Neuroblastoma No 3 2 0.95
Small cell lung carcinoma No 2 2 2.90
Colorectal adenocarcinoma No 4 2 0.87
Prostate adenocarcinoma No 4 1 0.41
Multiple myeloma No 1 1 1.45
Lower grade glioma No 1 1 0.59
Hepatocarcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 6 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence