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MTRR has not been detected as a mutational cancer driver

MTRR
Ensembl id ENSG00000124275
Mutated samples
Coding Sequence 98 (1.4%)
Protein Affecting 30 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MTRR gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 13 5 1.36
Breast carcinoma No 12 4 0.35
Head and neck squamous cell carcinoma No 10 4 1.07
Lung squamous cell carcinoma No 8 3 1.72
Lung adenocarcinoma No 6 2 0.51
Renal clear cell carcinoma No 3 2 0.48
Serous ovarian adenocarcinoma No 4 2 0.63
Stomach adenocarcinoma No 9 2 1.24
Small cell lung carcinoma No 3 2 2.90
Uterine corpus endometrioid carcinoma No 5 1 0.43
Lower grade glioma No 1 1 0.59
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 3 1 0.68
Hepatocarcinoma No 3 0 0.00
Bladder carcinoma No 7 0 0.00
Acute myeloid leukemia No 1 0 0.00
Pancreas adenocarcinoma No 2 0 0.00
Thyroid carcinoma No 1 0 0.00
Neuroblastoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Colorectal adenocarcinoma No 2 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence