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MPL × Head and Neck Squamous Cell Carcinoma ×

MPL is detected as a mutational cancer driver in Head and Neck Squamous Cell Carcinoma

MPL reports in Head and Neck Squamous Cell Carcinoma (HNSC)

Cancer type details
Head and Neck Squamous Cell Carcinoma
Cohorts 6
Samples 818
Mutations 2,112,343
Driver genes 80
Gene details
MPL
Ensembl ID ENSG00000117400
Transcript ID ENST00000372470
Protein ID ENSP00000361548
Cohorts where is driver 1
Mutated samples 4
Mutated samples (%) 0.49
Mutations 7
Mode of action Ambiguous
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence