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MIOS has not been detected as a mutational cancer driver

MIOS
Ensembl id ENSG00000164654
Mutated samples
Coding Sequence 56 (0.8%)
Protein Affecting 37 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MIOS gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 9 8 2.05
Lung squamous cell carcinoma No 8 4 2.30
Cutaneous melanoma No 9 4 1.08
Head and neck squamous cell carcinoma No 6 4 1.07
Bladder carcinoma No 3 3 3.06
Stomach adenocarcinoma No 5 3 1.86
Breast carcinoma No 3 2 0.17
Neuroblastoma No 2 2 0.95
Prostate adenocarcinoma No 1 1 0.41
Renal clear cell carcinoma No 3 1 0.24
Uterine corpus endometrioid carcinoma No 2 1 0.43
Chronic lymphocytic leukemia No 1 1 0.34
Multiple myeloma No 1 1 1.45
Diffuse B cell lymphoma No 1 1 4.35
Glioblastoma multiforme No 1 1 0.26
Colorectal adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence