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MICALL2 has not been detected as a mutational cancer driver

MICALL2
Ensembl id ENSG00000164877
Mutated samples
Coding Sequence 60 (0.9%)
Protein Affecting 39 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MICALL2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 22 14 3.79
Lung squamous cell carcinoma No 5 4 2.30
Bladder carcinoma No 3 3 3.06
Renal clear cell carcinoma No 4 3 0.72
Stomach adenocarcinoma No 3 3 1.86
Lung adenocarcinoma No 2 2 0.51
Breast carcinoma No 3 2 0.17
Serous ovarian adenocarcinoma No 2 2 0.63
Esophageal carcinoma No 5 2 1.37
Prostate adenocarcinoma No 1 1 0.41
Uterine corpus endometrioid carcinoma No 1 1 0.43
Head and neck squamous cell carcinoma No 3 1 0.27
Glioblastoma multiforme No 2 1 0.26
Hepatocarcinoma No 2 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence