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MIB1 has not been detected as a mutational cancer driver

MIB1
Ensembl id ENSG00000101752
Mutated samples
Coding Sequence 71 (1.0%)
Protein Affecting 52 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MIB1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 13 8 2.17
Breast carcinoma No 6 6 0.52
Serous ovarian adenocarcinoma No 5 5 1.58
Head and neck squamous cell carcinoma No 6 5 1.33
Lung adenocarcinoma No 4 4 1.02
Stomach adenocarcinoma No 5 4 2.48
Glioblastoma multiforme No 5 4 1.06
Bladder carcinoma No 4 3 3.06
Esophageal carcinoma No 3 3 2.05
Hepatocarcinoma No 2 2 2.22
Lung squamous cell carcinoma No 3 2 1.15
Uterine corpus endometrioid carcinoma No 3 2 0.87
Small cell lung carcinoma No 3 2 2.90
Thyroid carcinoma No 1 1 0.31
Colorectal adenocarcinoma No 1 1 0.44
Medulloblastoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Lower grade glioma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence