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MGAT4C has not been detected as a mutational cancer driver

MGAT4C
Ensembl id ENSG00000182050
Mutated samples
Coding Sequence 101 (1.5%)
Protein Affecting 69 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MGAT4C gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 34 26 7.05
Lung adenocarcinoma No 11 9 2.30
Lung squamous cell carcinoma No 5 4 2.30
Prostate adenocarcinoma No 3 3 1.23
Serous ovarian adenocarcinoma No 4 3 0.95
Glioblastoma multiforme No 3 3 0.79
Breast carcinoma No 2 2 0.17
Renal clear cell carcinoma No 2 2 0.48
Uterine corpus endometrioid carcinoma No 3 2 0.87
Chronic lymphocytic leukemia No 11 2 0.69
Lower grade glioma No 2 2 1.18
Stomach adenocarcinoma No 2 2 1.24
Small cell lung carcinoma No 2 2 2.90
Head and neck squamous cell carcinoma No 2 2 0.53
Esophageal carcinoma No 3 2 1.37
Hepatocarcinoma No 5 1 1.11
Acute myeloid leukemia No 1 1 0.51
Acute lymphocytic leukemia No 1 1 0.82
Pylocytic astrocytoma No 4 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence