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MFNG is detected as a mutational cancer driver in 1 cancer type: Cutaneous melanoma

MFNG
Ensembl id ENSG00000100060
Mutated samples
Coding Sequence 25 (0.4%)
Protein Affecting 19 (0.3%)
Mode of action Activating
Known driver No
Cancer type Signals (Biases)
CM F
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MFNG gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma Yes 17 14 3.79
Lung squamous cell carcinoma No 2 1 0.57
Uterine corpus endometrioid carcinoma No 1 1 0.43
Stomach adenocarcinoma No 3 1 0.62
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 1 1 0.68
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence