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MAPK8IP3 has not been detected as a mutational cancer driver

MAPK8IP3
Ensembl id ENSG00000138834
Mutated samples
Coding Sequence 101 (1.5%)
Protein Affecting 66 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MAPK8IP3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 23 11 2.98
Lung adenocarcinoma No 8 6 1.53
Stomach adenocarcinoma No 10 6 3.73
Head and neck squamous cell carcinoma No 8 6 1.60
Bladder carcinoma No 6 5 5.10
Uterine corpus endometrioid carcinoma No 7 5 2.17
Breast carcinoma No 5 4 0.35
Lung squamous cell carcinoma No 7 4 2.30
Small cell lung carcinoma No 4 4 5.80
Medulloblastoma No 3 3 1.43
Glioblastoma multiforme No 4 3 0.79
Esophageal carcinoma No 4 2 1.37
Prostate adenocarcinoma No 2 1 0.41
Pancreas adenocarcinoma No 2 1 0.47
Renal clear cell carcinoma No 1 1 0.24
Multiple myeloma No 1 1 1.45
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 1 1 0.32
Colorectal adenocarcinoma No 1 1 0.44
Thyroid carcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence