Top
LGR6 has not been detected as a mutational cancer driver

LGR6
Ensembl id ENSG00000133067
Mutated samples
Coding Sequence 91 (1.3%)
Protein Affecting 57 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all LGR6 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 39 20 5.42
Lung adenocarcinoma No 12 10 2.56
Head and neck squamous cell carcinoma No 6 4 1.07
Breast carcinoma No 4 3 0.26
Uterine corpus endometrioid carcinoma No 3 3 1.30
Serous ovarian adenocarcinoma No 3 3 0.95
Renal clear cell carcinoma No 2 2 0.48
Stomach adenocarcinoma No 2 2 1.24
Colorectal adenocarcinoma No 4 2 0.87
Esophageal carcinoma No 2 2 1.37
Bladder carcinoma No 1 1 1.02
Lung squamous cell carcinoma No 2 1 0.57
Pancreas adenocarcinoma No 1 1 0.47
Multiple myeloma No 1 1 1.45
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 3 1 0.26
Prostate adenocarcinoma No 2 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence