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LETMD1 has not been detected as a mutational cancer driver

LETMD1
Ensembl id ENSG00000050426
Mutated samples
Coding Sequence 42 (0.6%)
Protein Affecting 24 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all LETMD1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Bladder carcinoma No 3 3 3.06
Breast carcinoma No 5 3 0.26
Renal clear cell carcinoma No 3 3 0.72
Cutaneous melanoma No 7 3 0.81
Lung adenocarcinoma No 3 2 0.51
Lower grade glioma No 2 2 1.18
Stomach adenocarcinoma No 5 2 1.24
Glioblastoma multiforme No 3 2 0.53
Hepatocarcinoma No 2 1 1.11
Thyroid carcinoma No 1 1 0.31
Uterine corpus endometrioid carcinoma No 2 1 0.43
Small cell lung carcinoma No 2 1 1.45
Acute myeloid leukemia No 1 0 0.00
Multiple myeloma No 1 0 0.00
Diffuse B cell lymphoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence