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LCTL has not been detected as a mutational cancer driver

LCTL
Ensembl id ENSG00000188501
Mutated samples
Coding Sequence 49 (0.7%)
Protein Affecting 38 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all LCTL gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 13 12 3.25
Bladder carcinoma No 4 4 4.08
Lung adenocarcinoma No 6 3 0.77
Breast carcinoma No 3 3 0.26
Lung squamous cell carcinoma No 4 3 1.72
Uterine corpus endometrioid carcinoma No 3 2 0.87
Serous ovarian adenocarcinoma No 2 2 0.63
Stomach adenocarcinoma No 2 2 1.24
Prostate adenocarcinoma No 1 1 0.41
Hepatocarcinoma No 1 1 1.11
Renal clear cell carcinoma No 1 1 0.24
Colorectal adenocarcinoma No 2 1 0.44
Head and neck squamous cell carcinoma No 2 1 0.27
Diffuse B cell lymphoma No 1 1 4.35
Glioblastoma multiforme No 1 1 0.26
Thyroid carcinoma No 1 0 0.00
Esophageal carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence