KRAS is detected as a mutational cancer driver in Lung Adenocarcinoma
KRAS reports in Lung Adenocarcinoma (LUAD)
Cancer type details
Lung Adenocarcinoma |
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Cohorts
6
Samples 1,215 Mutations 1,839,527 Driver genes 76 |
Gene details
KRAS |
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Ensembl ID
ENSG00000133703
Transcript ID ENST00000256078 Protein ID ENSP00000256078 |
Cohorts where is driver
6
Mutated samples 289 Mutated samples (%) 23.79 Mutations 297 |
Mode of action Activating |
Known driver True |
Method signals per Cohort
Cohort | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
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LUAD (Lung Adenocarcinoma) | 1692 | 27 | 1.60 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Samples (%) | Consequence | Driver | Driver score |
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