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KRAS is detected as a mutational cancer driver in Acute Myeloid Leukemia

KRAS reports in Acute Myeloid Leukemia (AML)

Cancer type details
Acute Myeloid Leukemia
Cohorts 9
Samples 661
Mutations 295,755
Driver genes 62
Gene details
KRAS
Ensembl ID ENSG00000133703
Transcript ID ENST00000256078
Protein ID ENSP00000256078
Cohorts where is driver 5
Mutated samples 23
Mutated samples (%) 3.48
Mutations 25
Mode of action Activating
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence