KLK7 has not been detected as a mutational cancer driver
| KLK7 |
|---|
| Ensembl id ENSG00000169035 |
| Mutated samples
Coding Sequence 41 (0.6%) Protein Affecting 28 (0.4%) |
| Mode of action Unclassified |
| Known driver No |
| Cancer type | Signals (Biases) |
|---|
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all KLK7 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.
| Cancer type | Driver | Mutated samples (CS) | Mutated samples (PAM) | % Mutated samples (PAM) |
|---|---|---|---|---|
| Cutaneous melanoma | No | 17 | 13 | 3.52 |
| Lung adenocarcinoma | No | 6 | 4 | 1.02 |
| Breast carcinoma | No | 3 | 2 | 0.17 |
| Uterine corpus endometrioid carcinoma | No | 2 | 2 | 0.87 |
| Serous ovarian adenocarcinoma | No | 2 | 2 | 0.63 |
| Small cell lung carcinoma | No | 2 | 2 | 2.90 |
| Hepatocarcinoma | No | 2 | 1 | 1.11 |
| Acute myeloid leukemia | No | 1 | 1 | 0.51 |
| Lung squamous cell carcinoma | No | 3 | 1 | 0.57 |
| Prostate adenocarcinoma | No | 1 | 0 | 0.00 |
| Stomach adenocarcinoma | No | 1 | 0 | 0.00 |
| Colorectal adenocarcinoma | No | 1 | 0 | 0.00 |
Choose a transcript:
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.
| Variant Locus | Samples | AA pos | AA change | Consequence |
|---|