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KLK7 has not been detected as a mutational cancer driver

KLK7
Ensembl id ENSG00000169035
Mutated samples
Coding Sequence 41 (0.6%)
Protein Affecting 28 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all KLK7 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 17 13 3.52
Lung adenocarcinoma No 6 4 1.02
Breast carcinoma No 3 2 0.17
Uterine corpus endometrioid carcinoma No 2 2 0.87
Serous ovarian adenocarcinoma No 2 2 0.63
Small cell lung carcinoma No 2 2 2.90
Hepatocarcinoma No 2 1 1.11
Acute myeloid leukemia No 1 1 0.51
Lung squamous cell carcinoma No 3 1 0.57
Prostate adenocarcinoma No 1 0 0.00
Stomach adenocarcinoma No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence