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KCNJ12 has not been detected as a mutational cancer driver

KCNJ12
Ensembl id ENSG00000184185
Mutated samples
Coding Sequence 127 (1.9%)
Protein Affecting 82 (1.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all KCNJ12 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 39 16 4.34
Lung adenocarcinoma No 16 11 2.81
Stomach adenocarcinoma No 11 10 6.21
Lung squamous cell carcinoma No 10 7 4.02
Head and neck squamous cell carcinoma No 10 7 1.87
Breast carcinoma No 7 6 0.52
Esophageal carcinoma No 6 5 3.42
Renal clear cell carcinoma No 4 3 0.72
Small cell lung carcinoma No 3 3 4.35
Glioblastoma multiforme No 7 3 0.79
Bladder carcinoma No 2 2 2.04
Colorectal adenocarcinoma No 2 2 0.87
Prostate adenocarcinoma No 1 1 0.41
Medulloblastoma No 1 1 0.48
Uterine corpus endometrioid carcinoma No 2 1 0.43
Non small cell lung carcinoma No 3 1 3.23
Chronic lymphocytic leukemia No 1 1 0.34
Multiple myeloma No 1 1 1.45
Lower grade glioma No 1 1 0.59
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence