Top
KCNB2 has not been detected as a mutational cancer driver

KCNB2
Ensembl id ENSG00000182674
Mutated samples
Coding Sequence 229 (3.4%)
Protein Affecting 164 (2.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all KCNB2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 93 64 17.34
Lung adenocarcinoma No 21 17 4.35
Head and neck squamous cell carcinoma No 21 13 3.47
Stomach adenocarcinoma No 10 9 5.59
Breast carcinoma No 11 8 0.70
Colorectal adenocarcinoma No 9 7 3.06
Glioblastoma multiforme No 8 7 1.85
Lung squamous cell carcinoma No 6 6 3.45
Esophageal carcinoma No 8 6 4.11
Prostate adenocarcinoma No 5 5 2.06
Renal clear cell carcinoma No 5 5 1.20
Hepatocarcinoma No 4 4 4.44
Lower grade glioma No 3 3 1.78
Bladder carcinoma No 5 2 2.04
Pancreas adenocarcinoma No 2 2 0.93
Uterine corpus endometrioid carcinoma No 3 2 0.87
Small cell lung carcinoma No 2 2 2.90
Medulloblastoma No 1 1 0.48
Thyroid carcinoma No 1 1 0.31
Chronic lymphocytic leukemia No 6 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
Pylocytic astrocytoma No 3 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence