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JMJD1C has not been detected as a mutational cancer driver

JMJD1C
Ensembl id ENSG00000171988
Mutated samples
Coding Sequence 127 (1.9%)
Protein Affecting 93 (1.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all JMJD1C gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 23 15 4.07
Lung adenocarcinoma No 15 13 3.32
Head and neck squamous cell carcinoma No 13 12 3.20
Stomach adenocarcinoma No 10 8 4.97
Lung squamous cell carcinoma No 7 6 3.45
Renal clear cell carcinoma No 7 6 1.44
Breast carcinoma No 5 5 0.44
Uterine corpus endometrioid carcinoma No 8 5 2.17
Serous ovarian adenocarcinoma No 6 5 1.58
Thyroid carcinoma No 5 4 1.24
Colorectal adenocarcinoma No 3 3 1.31
Bladder carcinoma No 2 2 2.04
Small cell lung carcinoma No 2 2 2.90
Esophageal carcinoma No 3 2 1.37
Acute myeloid leukemia No 1 1 0.51
Non small cell lung carcinoma No 3 1 3.23
Lower grade glioma No 1 1 0.59
Glioblastoma multiforme No 3 1 0.26
Acute lymphocytic leukemia No 1 1 0.82
Prostate adenocarcinoma No 2 0 0.00
Hepatocarcinoma No 3 0 0.00
Medulloblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence