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INPP5F has not been detected as a mutational cancer driver

INPP5F
Ensembl id ENSG00000198825
Mutated samples
Coding Sequence 64 (0.9%)
Protein Affecting 44 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all INPP5F gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 12 8 2.17
Bladder carcinoma No 7 5 5.10
Uterine corpus endometrioid carcinoma No 6 4 1.74
Stomach adenocarcinoma No 4 4 2.48
Head and neck squamous cell carcinoma No 6 4 1.07
Breast carcinoma No 5 3 0.26
Lung adenocarcinoma No 3 2 0.51
Hepatocarcinoma No 2 2 2.22
Renal clear cell carcinoma No 3 2 0.48
Thyroid carcinoma No 2 2 0.62
Serous ovarian adenocarcinoma No 3 2 0.63
Lung squamous cell carcinoma No 1 1 0.57
Pancreas adenocarcinoma No 1 1 0.47
Neuroblastoma No 2 1 0.48
Multiple myeloma No 2 1 1.45
Small cell lung carcinoma No 1 1 1.45
Esophageal carcinoma No 2 1 0.68
Chronic lymphocytic leukemia No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence