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HOXA5 has not been detected as a mutational cancer driver

HOXA5
Ensembl id ENSG00000106004
Mutated samples
Coding Sequence 55 (0.8%)
Protein Affecting 22 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all HOXA5 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 13 9 2.30
Cutaneous melanoma No 14 5 1.36
Breast carcinoma No 5 3 0.26
Stomach adenocarcinoma No 5 2 1.24
Multiple myeloma No 1 1 1.45
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 1 1 0.44
Hepatocarcinoma No 1 0 0.00
Lung squamous cell carcinoma No 2 0 0.00
Thyroid carcinoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
Head and neck squamous cell carcinoma No 1 0 0.00
Glioblastoma multiforme No 4 0 0.00
Esophageal carcinoma No 2 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence