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HOXA3 has not been detected as a mutational cancer driver

HOXA3
Ensembl id ENSG00000105997
Mutated samples
Coding Sequence 160 (2.4%)
Protein Affecting 36 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all HOXA3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 43 14 3.79
Lung adenocarcinoma No 30 7 1.79
Lung squamous cell carcinoma No 12 4 2.30
Breast carcinoma No 14 3 0.26
Stomach adenocarcinoma No 12 3 1.86
Bladder carcinoma No 3 2 2.04
Esophageal carcinoma No 8 2 1.37
Small cell lung carcinoma No 4 1 1.45
Hepatocarcinoma No 8 0 0.00
Thyroid carcinoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 9 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Multiple myeloma No 1 0 0.00
Lower grade glioma No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
Colorectal adenocarcinoma No 2 0 0.00
Head and neck squamous cell carcinoma No 3 0 0.00
Glioblastoma multiforme No 5 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence