Top
HOXA2 has not been detected as a mutational cancer driver

HOXA2
Ensembl id ENSG00000105996
Mutated samples
Coding Sequence 67 (1.0%)
Protein Affecting 27 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all HOXA2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 13 7 1.79
Cutaneous melanoma No 18 7 1.90
Breast carcinoma No 7 5 0.44
Bladder carcinoma No 4 2 2.04
Lung squamous cell carcinoma No 3 1 0.57
Renal clear cell carcinoma No 1 1 0.24
Serous ovarian adenocarcinoma No 5 1 0.32
Stomach adenocarcinoma No 4 1 0.62
Head and neck squamous cell carcinoma No 2 1 0.27
Glioblastoma multiforme No 1 1 0.26
Hepatocarcinoma No 2 0 0.00
Neuroblastoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 2 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
Esophageal carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence