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HLTF has not been detected as a mutational cancer driver

HLTF
Ensembl id ENSG00000071794
Mutated samples
Coding Sequence 63 (0.9%)
Protein Affecting 44 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all HLTF gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 6 6 1.53
Lung squamous cell carcinoma No 6 6 3.45
Cutaneous melanoma No 12 6 1.63
Head and neck squamous cell carcinoma No 9 6 1.60
Uterine corpus endometrioid carcinoma No 6 3 1.30
Stomach adenocarcinoma No 3 3 1.86
Glioblastoma multiforme No 3 3 0.79
Breast carcinoma No 5 2 0.17
Renal clear cell carcinoma No 2 2 0.48
Hepatocarcinoma No 1 1 1.11
Bladder carcinoma No 1 1 1.02
Pancreas adenocarcinoma No 1 1 0.47
Chronic lymphocytic leukemia No 1 1 0.34
Multiple myeloma No 1 1 1.45
Small cell lung carcinoma No 2 1 1.45
Colorectal adenocarcinoma No 2 1 0.44
Prostate adenocarcinoma No 1 0 0.00
Lower grade glioma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence