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HIST1H2BH has not been detected as a mutational cancer driver

HIST1H2BH
Ensembl id ENSG00000197459
Mutated samples
Coding Sequence 60 (0.9%)
Protein Affecting 22 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all HIST1H2BH gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Head and neck squamous cell carcinoma No 11 5 1.33
Lung adenocarcinoma No 4 3 0.77
Breast carcinoma No 9 3 0.26
Cutaneous melanoma No 12 3 0.81
Lung squamous cell carcinoma No 4 2 1.15
Serous ovarian adenocarcinoma No 3 2 0.63
Prostate adenocarcinoma No 2 1 0.41
Uterine corpus endometrioid carcinoma No 2 1 0.43
Colorectal adenocarcinoma No 1 1 0.44
Esophageal carcinoma No 3 1 0.68
Bladder carcinoma No 2 0 0.00
Lower grade glioma No 1 0 0.00
Stomach adenocarcinoma No 3 0 0.00
Small cell lung carcinoma No 1 0 0.00
Glioblastoma multiforme No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence