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HIST1H2BD has not been detected as a mutational cancer driver

HIST1H2BD
Ensembl id ENSG00000158373
Mutated samples
Coding Sequence 83 (1.2%)
Protein Affecting 25 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all HIST1H2BD gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Uterine corpus endometrioid carcinoma No 9 6 2.61
Breast carcinoma No 7 4 0.35
Head and neck squamous cell carcinoma No 9 4 1.07
Cutaneous melanoma No 12 3 0.81
Lung squamous cell carcinoma No 5 2 1.15
Hepatocarcinoma No 2 1 1.11
Bladder carcinoma No 4 1 1.02
Thyroid carcinoma No 4 1 0.31
Neuroblastoma No 1 1 0.48
Serous ovarian adenocarcinoma No 4 1 0.32
Small cell lung carcinoma No 2 1 1.45
Lung adenocarcinoma No 6 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 6 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Stomach adenocarcinoma No 3 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
Diffuse B cell lymphoma No 3 0 0.00
Esophageal carcinoma No 2 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence