HIST1H2AK has not been detected as a mutational cancer driver

Ensembl id ENSG00000184348
Mutated samples
Coding Sequence 31 (0.5%)
Protein Affecting 18 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all HIST1H2AK gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 5 4 0.35
Lung squamous cell carcinoma No 4 3 1.72
Cutaneous melanoma No 2 2 0.54
Head and neck squamous cell carcinoma No 5 2 0.53
Esophageal carcinoma No 2 2 1.37
Bladder carcinoma No 1 1 1.02
Pancreas adenocarcinoma No 1 1 0.47
Renal clear cell carcinoma No 1 1 0.24
Uterine corpus endometrioid carcinoma No 3 1 0.43
Chronic lymphocytic leukemia No 1 1 0.34
Prostate adenocarcinoma No 2 0 0.00
Lung adenocarcinoma No 1 0 0.00
Stomach adenocarcinoma No 2 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence