HIP1R has not been detected as a mutational cancer driver

Ensembl id ENSG00000130787
Mutated samples
Coding Sequence 50 (0.7%)
Protein Affecting 27 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all HIP1R gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Bladder carcinoma No 7 4 4.08
Cutaneous melanoma No 13 4 1.08
Uterine corpus endometrioid carcinoma No 5 4 1.74
Renal clear cell carcinoma No 5 3 0.72
Lung adenocarcinoma No 3 2 0.51
Breast carcinoma No 3 2 0.17
Stomach adenocarcinoma No 4 2 1.24
Esophageal carcinoma No 2 2 1.37
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 2 1 0.44
Head and neck squamous cell carcinoma No 2 1 0.27
Glioblastoma multiforme No 2 1 0.26
Serous ovarian adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence