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GIT1 has not been detected as a mutational cancer driver

GIT1
Ensembl id ENSG00000108262
Mutated samples
Coding Sequence 51 (0.8%)
Protein Affecting 22 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GIT1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 15 6 1.63
Bladder carcinoma No 6 3 3.06
Renal clear cell carcinoma No 4 3 0.72
Breast carcinoma No 3 2 0.17
Uterine corpus endometrioid carcinoma No 2 2 0.87
Stomach adenocarcinoma No 4 2 1.24
Head and neck squamous cell carcinoma No 5 2 0.53
Neuroblastoma No 1 1 0.48
Colorectal adenocarcinoma No 1 1 0.44
Prostate adenocarcinoma No 1 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
Small cell lung carcinoma No 1 0 0.00
Glioblastoma multiforme No 2 0 0.00
Esophageal carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence