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GFI1 has not been detected as a mutational cancer driver

GFI1
Ensembl id ENSG00000162676
Mutated samples
Coding Sequence 22 (0.3%)
Protein Affecting 14 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GFI1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung squamous cell carcinoma No 3 3 1.72
Head and neck squamous cell carcinoma No 2 2 0.53
Lung adenocarcinoma No 2 1 0.26
Breast carcinoma No 1 1 0.09
Thyroid carcinoma No 1 1 0.31
Non small cell lung carcinoma No 1 1 3.23
Chronic lymphocytic leukemia No 1 1 0.34
Serous ovarian adenocarcinoma No 1 1 0.32
Stomach adenocarcinoma No 2 1 0.62
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 1 1 0.26
Prostate adenocarcinoma No 1 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Cutaneous melanoma No 4 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence