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GCC1 has not been detected as a mutational cancer driver

GCC1
Ensembl id ENSG00000179562
Mutated samples
Coding Sequence 105 (1.5%)
Protein Affecting 33 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GCC1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 13 5 1.28
Head and neck squamous cell carcinoma No 11 5 1.33
Uterine corpus endometrioid carcinoma No 11 4 1.74
Renal clear cell carcinoma No 3 3 0.72
Stomach adenocarcinoma No 8 3 1.86
Breast carcinoma No 6 2 0.17
Lung squamous cell carcinoma No 10 2 1.15
Cutaneous melanoma No 17 2 0.54
Serous ovarian adenocarcinoma No 4 2 0.63
Prostate adenocarcinoma No 5 1 0.41
Neuroblastoma No 2 1 0.48
Small cell lung carcinoma No 5 1 1.45
Glioblastoma multiforme No 3 1 0.26
Esophageal carcinoma No 1 1 0.68
Hepatocarcinoma No 2 0 0.00
Thyroid carcinoma No 1 0 0.00
Multiple myeloma No 2 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence