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FOLH1 has not been detected as a mutational cancer driver

FOLH1
Ensembl id ENSG00000086205
Mutated samples
Coding Sequence 104 (1.5%)
Protein Affecting 76 (1.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FOLH1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 32 21 5.69
Lung squamous cell carcinoma No 13 11 6.32
Lung adenocarcinoma No 13 10 2.56
Head and neck squamous cell carcinoma No 11 8 2.13
Breast carcinoma No 8 6 0.52
Small cell lung carcinoma No 6 6 8.70
Esophageal carcinoma No 4 4 2.74
Stomach adenocarcinoma No 4 3 1.86
Bladder carcinoma No 4 2 2.04
Hepatocarcinoma No 2 1 1.11
Uterine corpus endometrioid carcinoma No 1 1 0.43
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 2 1 0.26
Acute lymphocytic leukemia No 1 1 0.82
Lower grade glioma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence