IntOGen - FHIT gene cancer mutations

FHIT is detected as a mutational cancer driver

FHIT reports

Methods
Mutation distribution

Gene details

FHIT
Ensembl ID ENSG00000189283 Transcript ID ENST00000492590 Protein ID ENSP00000418582
Cancer types where is driver 1 Cohorts where is driver 1 Mutated samples 3 Mutations 97
Mode of action Activating
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence