Top

FAT1 is detected as a mutational cancer driver in Endometrial Carcinoma

FAT1 reports in Endometrial Carcinoma (UCEC)

Cancer type details
Endometrial Carcinoma
Cohorts 4
Samples 691
Mutations 3,631,382
Driver genes 69
Gene details
FAT1
Ensembl ID ENSG00000083857
Transcript ID ENST00000441802
Protein ID ENSP00000406229
Cohorts where is driver 2
Mutated samples 52
Mutated samples (%) 7.53
Mutations 74
Mode of action Loss of function
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence