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EZH2 × Acute Lymphoblastic Leukemia ×

EZH2 is detected as a mutational cancer driver in Acute Lymphoblastic Leukemia

EZH2 reports in Acute Lymphoblastic Leukemia (ALL)

Cancer type details
Acute Lymphoblastic Leukemia
Cohorts 5
Samples 363
Mutations 202,546
Driver genes 28
Gene details
EZH2
Ensembl ID ENSG00000106462
Transcript ID ENST00000320356
Protein ID ENSP00000320147
Cohorts where is driver 1
Mutated samples 3
Mutated samples (%) 0.83
Mutations 3
Mode of action Activating
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence