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EYA1 has not been detected as a mutational cancer driver

EYA1
Ensembl id ENSG00000104313
Mutated samples
Coding Sequence 106 (1.6%)
Protein Affecting 80 (1.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all EYA1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 37 30 8.13
Head and neck squamous cell carcinoma No 10 10 2.67
Lung adenocarcinoma No 12 9 2.30
Breast carcinoma No 7 7 0.61
Stomach adenocarcinoma No 9 6 3.73
Serous ovarian adenocarcinoma No 4 4 1.27
Lung squamous cell carcinoma No 3 3 1.72
Colorectal adenocarcinoma No 3 3 1.31
Chronic lymphocytic leukemia No 6 2 0.69
Multiple myeloma No 3 2 2.90
Glioblastoma multiforme No 2 2 0.53
Bladder carcinoma No 1 1 1.02
Uterine corpus endometrioid carcinoma No 3 1 0.43
Hepatocarcinoma No 2 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
Esophageal carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence