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EPHA3 × Invasive Breast Carcinoma ×

EPHA3 is detected as a mutational cancer driver in Invasive Breast Carcinoma

EPHA3 reports in Invasive Breast Carcinoma (BRCA)

Cancer type details
Invasive Breast Carcinoma
Cohorts 14
Samples 3,201
Mutations 19,887,724
Driver genes 117
Gene details
EPHA3
Ensembl ID ENSG00000044524
Transcript ID ENST00000336596
Protein ID ENSP00000337451
Cohorts where is driver 1
Mutated samples 12
Mutated samples (%) 0.37
Mutations 36
Mode of action Activating
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence