Top
EPG5 has not been detected as a mutational cancer driver

EPG5
Ensembl id ENSG00000152223
Mutated samples
Coding Sequence 129 (1.9%)
Protein Affecting 93 (1.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all EPG5 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 24 17 4.61
Lung adenocarcinoma No 15 14 3.58
Breast carcinoma No 13 10 0.87
Bladder carcinoma No 7 6 6.12
Lung squamous cell carcinoma No 10 6 3.45
Uterine corpus endometrioid carcinoma No 9 5 2.17
Small cell lung carcinoma No 6 5 7.25
Stomach adenocarcinoma No 8 4 2.48
Colorectal adenocarcinoma No 5 4 1.75
Head and neck squamous cell carcinoma No 5 4 1.07
Prostate adenocarcinoma No 3 3 1.23
Thyroid carcinoma No 4 3 0.93
Renal clear cell carcinoma No 3 2 0.48
Neuroblastoma No 2 2 0.95
Chronic lymphocytic leukemia No 3 2 0.69
Serous ovarian adenocarcinoma No 2 2 0.63
Glioblastoma multiforme No 2 2 0.53
Hepatocarcinoma No 2 1 1.11
Multiple myeloma No 1 1 1.45
Non small cell lung carcinoma No 2 0 0.00
Lower grade glioma No 2 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence