IntOGen - EML4 gene cancer mutations

EML4 is detected as a mutational cancer driver

EML4 reports

Methods
Mutation distribution

Gene details

EML4
Ensembl ID ENSG00000143924 Transcript ID ENST00000318522 Protein ID ENSP00000320663
Cancer types where is driver 2 Cohorts where is driver 2 Mutated samples 6 Mutations 183
Mode of action Ambiguous
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence