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EME2 has not been detected as a mutational cancer driver

EME2
Ensembl id ENSG00000197774
Mutated samples
Coding Sequence 55 (0.8%)
Protein Affecting 11 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all EME2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 7 2 0.51
Renal clear cell carcinoma No 5 2 0.48
Lung squamous cell carcinoma No 4 1 0.57
Pancreas adenocarcinoma No 1 1 0.47
Cutaneous melanoma No 10 1 0.27
Uterine corpus endometrioid carcinoma No 3 1 0.43
Stomach adenocarcinoma No 6 1 0.62
Head and neck squamous cell carcinoma No 3 1 0.27
Glioblastoma multiforme No 2 1 0.26
Prostate adenocarcinoma No 2 0 0.00
Bladder carcinoma No 3 0 0.00
Acute myeloid leukemia No 1 0 0.00
Breast carcinoma No 2 0 0.00
Thyroid carcinoma No 2 0 0.00
Lower grade glioma No 1 0 0.00
Small cell lung carcinoma No 2 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence